Change in Epidemiology of Creutzfeldt-Jakob Disease in the US, 2007-2020

Creutzfeldt-Jakob disease (CJD) is a rapidly progressive and universally fatal prion disease. Research on CJD in the US showed stable incidence from 1979 to 2006, though recent trends are not as well described. The incidence of sporadic CJD, the most common type, is higher among older patients. Due to aging populations worldwide, the epidemiology of CJD is evolving. We examined death certificate data from 2007 to 2020 to better understand recent US trends of CJD.

The full research letter is available in JAMA Internal Medicine.

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